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Figure 2 | BMC Genomics

Figure 2

From: Genomic analysis of the emergence of 20th century epidemic dysentery

Figure 2

Similarity of genes distributions across COG functional categories. a. Distribution of genes in COG functional categories for the entire pan-genome, the genes that were lost in some strains and the genes modified by non-synonymous substitutions (expressed in percentage of genes in each group versus total number of genes). Genes for whom no function could be assigned were left out (lost: 17.18%, non-synonymous: 7.92%, pan-genome: 18.75%). b. Genes lost and genes modified with non-synonymous substitutions tend to distribute across functional categories in a similar fashion as genes overall (Pearson correlation = 0.9097 and 0.9758 respectively) indicating that the loss or modification of genes are selected at random. Only one functional category contains more lost genes than expected: lipid metabolism. In contrast, the functions of genes that were gained do not reflect the distribution of genes overall across functional categories (Pearson correlation = 0.5087) (data not shown).

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