Phylogenetic relationship of nuclear receptors in Crassostrea gigas, Homo sapiens, Drosophila melanogaster, Caenorhabditis elegans and mollusc species. The alignment was constructed using the DBD plus portion of LBD and phylogenetic relationship was conducted by a Maximum likelihood (ML), Bayesian Inference and neighbour-joining (NJ) analyses. ML bootstrap support values (percentage of 1000 BS), Bayesian posterior probabilities (PPs) and NJ bootstrap support values (percentage of 1000 BS) are provided above the nodes separated by slash. Star indicates the node obtained from the Bayesian Inference and NJ analyses, which were different from that obtained by ML method. Highlighted clades display the six NR subfamilies, olive: NR1, pink: NR2, green: NR3, orange: NR4, dark blue: NR5, light blue: NR6. C. gigas NRs highlighted in red. Ac: Aplysia californica, Bg: Biomphalaria glabrata, Ce: C. elegans, Cg: C. gigas, Dm: D. melanogaster, Hs: H. sapiens, Lym: Lymnaea stagnalis, Mc: Marisa cornuarietis, Me: Mytilus edulis, Mg: Mytilus galloprovincialis, Nl: Nucella lapillus, Ov: Octopus vulgaris, Tc: Thais clavigera.