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Table 3 DAVID Gene Ontology (GO) functional annotation on the prostate tumor models during their transition from in vitro to in vivo growth

From: Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages - strategies for data mining in support of therapeutic studies

Accession Gene Ontology Term generated from DAVID analysis of human-RNA-only-binding probe sets Gene count PValue Fold enrichment Benjamini False discovery rate (%)
GO:0044421 extracellular region part 14 4.68E-07 5.33 4.12E-05 5.07E-04
GO:0005615 extracellular space 12 8.91E-07 6.40 3.92E-05 9.65E-04
GO:0005576 extracellular region 18 3.26E-06 3.27 9.55E-05 3.53E-03
GO:0005578 proteinaceous extracellular matrix 7 1.75E-04 7.99 3.84E-03 0.19
GO:0031012 extracellular matrix 7 2.63E-04 7.41 4.61E-03 0.28
GO:0009611 response to wounding 7 0.0019 5.10 0.6674 2.70
GO:0019932 second-messenger-mediated signaling 5 0.0027 8.22 0.5559 3.96
GO:0001568 blood vessel development 5 0.0032 7.89 0.4668 4.58
GO:0001944 vasculature development 5 0.0035 7.70 0.4022 4.99
GO:0005581 collagen 3 0.0039 31.30 0.0553 4.11
GO:0048870 cell motility 5 0.0071 6.30 0.4510 9.91
GO:0051674 localization of cell 5 0.0071 6.30 0.4510 9.91
GO:0008009 chemokine activity 3 0.0072 22.88 0.6673 8.26
GO:0006935 chemotaxis 4 0.0074 9.66 0.4245 10.41
GO:0042330 taxis 4 0.0074 9.66 0.4245 10.41
GO:0001501 skeletal system development 5 0.0081 6.06 0.4132 11.24
GO:0042379 chemokine receptor binding 3 0.0081 21.48 0.4633 9.29
GO:0005125 cytokine activity 4 0.0166 7.20 0.5732 18.13
GO:0005201 extracellular matrix structural constituent 3 0.0236 12.24 0.5992 24.90