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Table 3 DAVID Gene Ontology (GO) functional annotation on the prostate tumor models during their transition from in vitro to in vivo growth

From: Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages - strategies for data mining in support of therapeutic studies

Accession

Gene Ontology Term generated from DAVID analysis of human-RNA-only-binding probe sets

Gene count

PValue

Fold enrichment

Benjamini

False discovery rate (%)

GO:0044421

extracellular region part

14

4.68E-07

5.33

4.12E-05

5.07E-04

GO:0005615

extracellular space

12

8.91E-07

6.40

3.92E-05

9.65E-04

GO:0005576

extracellular region

18

3.26E-06

3.27

9.55E-05

3.53E-03

GO:0005578

proteinaceous extracellular matrix

7

1.75E-04

7.99

3.84E-03

0.19

GO:0031012

extracellular matrix

7

2.63E-04

7.41

4.61E-03

0.28

GO:0009611

response to wounding

7

0.0019

5.10

0.6674

2.70

GO:0019932

second-messenger-mediated signaling

5

0.0027

8.22

0.5559

3.96

GO:0001568

blood vessel development

5

0.0032

7.89

0.4668

4.58

GO:0001944

vasculature development

5

0.0035

7.70

0.4022

4.99

GO:0005581

collagen

3

0.0039

31.30

0.0553

4.11

GO:0048870

cell motility

5

0.0071

6.30

0.4510

9.91

GO:0051674

localization of cell

5

0.0071

6.30

0.4510

9.91

GO:0008009

chemokine activity

3

0.0072

22.88

0.6673

8.26

GO:0006935

chemotaxis

4

0.0074

9.66

0.4245

10.41

GO:0042330

taxis

4

0.0074

9.66

0.4245

10.41

GO:0001501

skeletal system development

5

0.0081

6.06

0.4132

11.24

GO:0042379

chemokine receptor binding

3

0.0081

21.48

0.4633

9.29

GO:0005125

cytokine activity

4

0.0166

7.20

0.5732

18.13

GO:0005201

extracellular matrix structural constituent

3

0.0236

12.24

0.5992

24.90