Evolution of the main TR γ clones from a patient with ALL, starting at diagnosis and diluted to decreasing concentrations of 10-2, 10-3, 10-4, and 10-5 (left part of the plot); and when the patient is followed at three time points (Fu1, Fu2, and Fu4, right part). Clones #01 and #02 are the two most abundant clones detected at diagnosis, and the other clones are among the five most abundant clones, for at least one sample. Clones D-1 to D-6 are found in at least two of the dilutions, but are never found in any sample that is not a dilution. The black and gray boxes below each point indicate the maximum resolution, depending on the number of reads of each sample (black: 1 read, absolute detection threshold; gray: 5 reads, detection threshold to consider that the clone is significant). A sequencing with more reads will improve these thresholds.