Table 3 Functional annotation clustering of genes upregulated in muscle from Iberian piglets

GO:0044255 ~ cellular lipid metabolic process

11

0.00007

PLAA, PTGES3, SAMD8, AGPAT5, ALOX5AP, SCD, EPHX2, PLA1A, GNPAT, ELOVL6, SIRT1

GO:0006644 ~ phospholipid metabolic process

4

0.034

PLAA, SAMD8, AGPAT5, PLA1A

GO:0019637 ~ organophosphate metabolic process

4

0.037

PLAA, SAMD8, AGPAT5, PLA1A

Annotation Cluster 2 Enrichment Score: 2.11

Count

P value ⁺

Genes

GO:0006350 ~ transcription

16

0.001

NFKBIZ, ZFP30, RBM4, AFF4, AFF3, ZNF143, SIRT1, CBFB, MAX, CNTF, ZNF326, IRF1, PHTF1, NFE2L1, DNTTIP2, MLLT3

GO:0006366 ~ transcription from RNA polymerase II promoter

5

0.001

MAX, AFF4, IRF1, NFE2L1, CBFB

GO:0032774 ~ RNA biosynthetic process

5

0.005

MAX, AFF4, IRF1, NFE2L1, CBFB

GO:0006351 ~ transcription, DNA-dependent

5

0.005

MAX, AFF4, IRF1, NFE2L1, CBFB

GO:0045449 ~ regulation of transcription

19

0.007

NFKBIZ, ZFP30, RBM4, AFF4, AFF3, ZNF143, SIRT1, CBFB, MAX, CNTF, NEDD4, ZNF326, AGT, TIAL1, IRF1, PHTF1, NFE2L1, DNTTIP2, MLLT3

Annotation Cluster 3 Enrichment Score: 1.69

Count

P value ⁺

Genes

GO:0006508 ~ proteolysis

13

0.003

CTSL2, ASB11, MYLIP, C4BPA, UBE2QL1, MARCH6, UBE2D4, CASP4, PSMD11, NEDD4, KLHL15, CASP7, RNF19B

GO:0019941 ~ modification-dependent protein catabolic process

9

0.004

UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6

GO:0043632 ~ modification-dependent macromolecule catabolic process

9

0.004

UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6

GO:0051603 ~ proteolysis involved in cellular protein catabolic process

9

0.005

UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6

GO:0044257 ~ cellular protein catabolic process

9

0.005

UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6

GO:0030163 ~ protein catabolic process

9

0.007

UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6

GO:0009057 ~ macromolecule catabolic process

10

0.008

NGLY1, UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6

GO:0044265 ~ cellular macromolecule catabolic process

9

0.014

UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6