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Table 3 Functional annotation clustering of genes upregulated in muscle from Iberian piglets

From: Longissimus dorsi transcriptome analysis of purebred and crossbred Iberian pigs differing in muscle characteristics

Annotation Cluster 1 Enrichment Score: 2.33 Count P value+ Genes
GO:0044255 ~ cellular lipid metabolic process 11 0.00007 PLAA, PTGES3, SAMD8, AGPAT5, ALOX5AP, SCD, EPHX2, PLA1A, GNPAT, ELOVL6, SIRT1
GO:0006644 ~ phospholipid metabolic process 4 0.034 PLAA, SAMD8, AGPAT5, PLA1A
GO:0019637 ~ organophosphate metabolic process 4 0.037 PLAA, SAMD8, AGPAT5, PLA1A
Annotation Cluster 2 Enrichment Score: 2.11 Count P value + Genes
GO:0006350 ~ transcription 16 0.001 NFKBIZ, ZFP30, RBM4, AFF4, AFF3, ZNF143, SIRT1, CBFB, MAX, CNTF, ZNF326, IRF1, PHTF1, NFE2L1, DNTTIP2, MLLT3
GO:0006366 ~ transcription from RNA polymerase II promoter 5 0.001 MAX, AFF4, IRF1, NFE2L1, CBFB
GO:0032774 ~ RNA biosynthetic process 5 0.005 MAX, AFF4, IRF1, NFE2L1, CBFB
GO:0006351 ~ transcription, DNA-dependent 5 0.005 MAX, AFF4, IRF1, NFE2L1, CBFB
GO:0045449 ~ regulation of transcription 19 0.007 NFKBIZ, ZFP30, RBM4, AFF4, AFF3, ZNF143, SIRT1, CBFB, MAX, CNTF, NEDD4, ZNF326, AGT, TIAL1, IRF1, PHTF1, NFE2L1, DNTTIP2, MLLT3
Annotation Cluster 3 Enrichment Score: 1.69 Count P value + Genes
GO:0006508 ~ proteolysis 13 0.003 CTSL2, ASB11, MYLIP, C4BPA, UBE2QL1, MARCH6, UBE2D4, CASP4, PSMD11, NEDD4, KLHL15, CASP7, RNF19B
GO:0019941 ~ modification-dependent protein catabolic process 9 0.004 UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6
GO:0043632 ~ modification-dependent macromolecule catabolic process 9 0.004 UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6
GO:0051603 ~ proteolysis involved in cellular protein catabolic process 9 0.005 UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6
GO:0044257 ~ cellular protein catabolic process 9 0.005 UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6
GO:0030163 ~ protein catabolic process 9 0.007 UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6
GO:0009057 ~ macromolecule catabolic process 10 0.008 NGLY1, UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6
GO:0044265 ~ cellular macromolecule catabolic process 9 0.014 UBE2D4, NEDD4, PSMD11, KLHL15, ASB11, RNF19B, UBE2QL1, MYLIP, MARCH6
  1. +P-value from modified Fisher exact score.