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Table 3 Summary of observed surviving LSP P mutants in the output pool

From: Disruption of Mycobacterium avium subsp. paratuberculosis-specific genes impairs in vivo fitness

Observed Survived Tn Depleted Total
Output - 0.2 × median    
LSPP 49 33 82
not LSPP 1711 650 2361
Total 1760 683 2443
Chi-square test P = 0.01   
Output - 0.1 × median    
LSPP 56 26 82
not LSPP 1972 389 2361
Total 2028 415 2443
Chi-square test P = 0.0003   
Output - 0.05 × median    
LSPP 69 13 82
not LSPP 2137 224 2361
Total 2206 237 2443
Chi-square test P = 0.06   
  1. Summary of observed surviving LSPP mutants in the output pool at different thresholds compared to expected values (values not shown), and the p value of corresponding chi-square test.