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Table 3 Summary of observed surviving LSP P mutants in the output pool

From: Disruption of Mycobacterium avium subsp. paratuberculosis-specific genes impairs in vivo fitness

Observed

Survived Tn

Depleted

Total

Output - 0.2 × median

   

LSPP

49

33

82

not LSPP

1711

650

2361

Total

1760

683

2443

Chi-square test

P = 0.01

  

Output - 0.1 × median

   

LSPP

56

26

82

not LSPP

1972

389

2361

Total

2028

415

2443

Chi-square test

P = 0.0003

  

Output - 0.05 × median

   

LSPP

69

13

82

not LSPP

2137

224

2361

Total

2206

237

2443

Chi-square test

P = 0.06

  
  1. Summary of observed surviving LSPP mutants in the output pool at different thresholds compared to expected values (values not shown), and the p value of corresponding chi-square test.