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Table 1 Frequencies of haplotypes directly observed by LHA in 2-SNP blocks from the CEU_TRIO (whole genome) and HNC_62 (whole exome; aggregated into normal and tumor tissues)

From: Direct observation of genomic heterogeneity through local haplotyping analysis

Subject

Total 2-blocks

Number of haplotypes in the block

  

0

1

2

3

4

NA12878*

225,139

86,719 (38%)

30,869 (14%)

103,339 (46%)

4,138 (2%)

73 (0%)

NA12891

224,079

75,756 (34%)

47,039 (21%)

96,263 (43%)

4,889 (2%)

132 (0%)

NA12892*

231,666

85,234 (37%)

50,738 (22%)

91,208 (39%)

4,394 (2%)

91 (0%)

HNC-normal

72,670

23,050 (32%)

8,535 (12%)

40,054 (55%)

1,006 (1.4%)

25 (0%)

HNC-tumor

73,591

23,100 (31%)

9,245 (13%)

40,005 (54%)

1,214 (1.6%)

27 (0%)

  1. *NA12878 has one block with 6 haplotypes. NA12892 has one block with 5 haplotypes.