Figure 3

COG Classification of B. fragilis 638R essential genes. Legend: A- RNA processing and modification, C-Energy production and conversion, D- Cell cycle control, cell division, chromosome partitioning, E- Amino acid transport and metabolism, F- Nucleotide transport and metabolism, G- Carbohydrate transport and metabolism, H- Coenzyme transport and metabolism, I- Lipid transport and metabolism, J- Translation, ribosomal structure and biogenesis, K- Transcription, L- Replication, recombination and repair, M- Cell wall/membrane/envelope biogenesis, N- Cell motility, O- Posttranslational modification, protein turnover, chaperones, P- Inorganic ion transport and metabolism, Q- Secondary metabolites biosynthesis, transport and catabolism, R- General function prediction only, T- Signal transduction mechanisms, U- Intracellular trafficking, secretion, and vesicular transport, V- Defense mechanisms, S- Function unknown, X- Essential genes not in COG.