Figure 5
Analysis of potential signatures of selection in the common population-specific (CPS) SNP-enriched windows. (A) Expected and observed number of iES (iHS enrichment score) enriched windows (see Methods for details) in YRI, LWK, JPT and CHINESE populations. The number which has been appended to the population code indicates the top nth percentage of iHS score considered (1 = top 1%; 5 = top 5% and 10 = top 10%). The corresponding p-values for enrichment are shown on the right axis. (B) Expected and observed occurrences of top 1%, 5% and 10% population branch statistic (PBS) scores amongst CPS SNP-enriched windows for YRI, LWK, JPT and CHINESE populations. A three letter population combination code (say YLJ) has been used to describe the 3 population set used for calculating the PBS score. The first letter (Y) indicates the population being analysed (YRI in this case). The CPS SNP-enriched windows are analysed for this population. The second letter (L) indicates the population to which it was compared (LWK here) and the third letter (J) indicates the outlier (JPT in this case). The number, appended with an underscore to each three letter dataset name indicates the top nth percentage of PBS score cut-off used for analysis (1 = top 1%, 5 = top 5% and 10 = top 10%).