Figure 5

P-value heatmaps for immune, cuticle, stress, P450, odorant binding and developmental genes. P-values are based on the overrepresentation analysis of defined gene sets (immune gene set [14], developmental gene set [8] and other gene sets based on annotation downloaded from the EnsemblMetazoa database, release 17 [65]) in the lists of significantly A) upregulated and B) downregulated genes for every of the twelve pairwise differential expression analyses; an asterisk indicates p<0.05 (Fisher’s Exact Test; p-value corrected for multiple testing according to the Benjamini Hochberg procedure). Significant up- and downregulation is based on Cufflinks analyses with the default q-value cutoff of 0.05 [60].