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Figure 6 | BMC Genomics

Figure 6

From: Improving analysis of transcription factor binding sites within ChIP-Seq data based on topological motif enrichment

Figure 6

Dinucleotide-environment view plots the dinucleotide enrichment of the dataset around the motif of interest. The x-axis shows the dinucleotide offset from the centre of the motif, and the y-axis is the proportion of the dinucleotide in the ChIP-Seq sequences. The STAT1 motif is the high frequency pattern in the centre of the plot. The sequence logo for STAT1 is above the high frequency pattern. (a) The subset of STAT1 ChIP-Seq peaks containing a STAT1 motif in the enrichment zone with a motif score greater than or equal to 85. The magenta box highlights the enrichment of dinucleotides in the flanking regions of STAT1 motifs proximal to the peakMax. (b) The subset of STAT1 peaks with a motif outside the enrichment zone and a motif score of 85 or greater. The magenta box highlights the lack of dinucleotide enrichment in the flanking regions of motifs found distal to the peakMax.

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