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Figure 8 | BMC Genomics

Figure 8

From: Improving analysis of transcription factor binding sites within ChIP-Seq data based on topological motif enrichment

Figure 8

Case study of ZNF143 DNA binding preferences. The sequence logo presents the binding site characteristics of ZNF143. (a) Dinucleotide-environment view of ZNF143 ChIP-Seq repeat-masked regions aligned on motifs with a motif score of 85 or greater. The x-axis is the nucleotide position and the y-axis is the frequency of the dinucleotide. The coloured lines each represent one of 16 dinucleotides, as specified in the plot legend. The vertical magenta lines frame the positions of the sequence logo. (b) Dinucleotide-environment view of ZNF143 canonical motifs with a motif score of >85. The x-axis is the nucleotide position and the y-axis is the frequency of the dinucleotide. The coloured lines each represent one of 16 dinucleotides, as specified in the plot legend. The orange horizontal line above the plot indicates the overlapping THAP11 binding profile.

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BMC Genomics

ISSN: 1471-2164

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