From: A new approach for efficient genotype imputation using information from relatives
Scenario | Structure of reference group | Reference size | Imputation method |
---|---|---|---|
3 k/6 k to 50 k | |||
A | Reference individuals were randomly selected after excluding parents and grandparents of the target group | 100, 500, 1,000, 1,500, 2,000, 3,000, 5,000, 10,000 | Population |
B | All parents and grandparents of the target group | 1,629 | Population |
C | As in B | 1,629 | Family + population |
D | All males including sires and grandsires of the target group | 64,429 | Population |
E | As in D | 64,429 | Family + population |
50 k to 300 k | |||
F | As in A | 100, 500, 1,000, 1,588 | Population |
G | Reference group consisted of all individuals | 1,733 | Population |
H | As in G | 1,733 | Family + population |