Figure 6From: Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathwaysComparison of spatial distribution of differentially expressed genes in TS23 control (A,C,E,G,I,K,M) and TS23 mutant (B,D,F,H,J,L,N,P) elbow joint, shoulder joint, humerus, radius and ulna. Cd44 (A-D) expression in the elbow joint (A-B), and the shoulder joint (C-D) (arrows in B and D indicate the position of joint-line cells based on cell morphology), Sfrp2 (E-H) expression in the elbow joint (E-F) (arrow indicates abnormal expression on the ventral side of the joint), and the shoulder joint (G-H), Wnt4 expression in the elbow joint (I-J), and the shoulder joint (K-L), Spp1 (K-N) expression in the humerus hypertrophic zone (hz) and perichondrium (p) (M-N) (the arrowhead in L indicates enlarged hypertropic chondrocytes), and in the ulna (u) and radius (r) (O-P). e epidermis. All scale bars are 100 μm.Back to article page