Table 3 Gene sets enriched in PCB 153 treated samples a
Reactome gene set | SIZE | NES | NOM p-val | FDR q-val |
|---|---|---|---|---|
SYNTHESIS_OF_DNA | 61 | 2.0 | 3.1E-03 | 0.09 |
DNA_STRAND_ELONGATION | 25 | 1.9 | 1.4E-02 | 0.05 |
M_G1_TRANSITION | 52 | 1.9 | 7.2E-03 | 0.04 |
S_PHASE | 74 | 1.9 | 7.1E-03 | 0.05 |
ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX | 40 | 1.9 | 0 | 0.04 |
ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | 26 | 1.9 | 3.0E-02 | 0.04 |
ORC1_REMOVAL_FROM_CHROMATIN | 41 | 1.8 | 0 | 0.05 |
ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS | 34 | 1.8 | 6.1E-03 | 0.06 |
SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 | 25 | 1.8 | 7.2E-03 | 0.05 |
G1_S_TRANSITION | 76 | 1.8 | 1.3E-02 | 0.05 |
ER_PHAGOSOME_PATHWAY | 30 | 1.7 | 4.1E-03 | 0.06 |
CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX | 32 | 1.7 | 3.0E-03 | 0.05 |
TRNA_AMINOACYLATION | 26 | 1.7 | 2.7E-02 | 0.05 |
SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 | 31 | 1.7 | 1.1E-02 | 0.05 |
MITOTIC_G1_G1_S_PHASES | 90 | 1.7 | 1.6E-02 | 0.05 |
VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | 25 | 1.7 | 1.0E-02 | 0.05 |
TRIGLYCERIDE_BIOSYNTHESIS | 30 | 1.7 | 9.1E-03 | 0.05 |
ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | 28 | 1.7 | 4.3E-02 | 0.06 |
GLOBAL_GENOMIC_NER_GG_NER | 25 | 1.7 | 1.7E-02 | 0.06 |
GenMAPP gene set | SIZE | NES | NOM p-val | FDR q-val |
DNA_REPLICATION_REACTOME | 29 | 2.0 | 0.021 | 0.03 |
AMINOACYL_TRNA_BIOSYNTHESIS | 15 | 1.9 | 0.020 | 0.03 |
G1_TO_S_CELL_CYCLE_REACTOME | 41 | 1.6 | 0.058 | 0.20 |
GLYCEROPHOSPHOLIPID_METABOLISM | 32 | 1.6 | 0.020 | 0.21 |
KEGG gene set | SIZE | NES | NOM p-val | FDR q-val |
DNA_REPLICATION | 30 | 1.9 | 0.027 | 0.04 |
NUCLEOTIDE_EXCISION_REPAIR | 31 | 1.6 | 0.025 | 0.24 |
OXIDATIVE_PHOSPHORYLATION | 50 | 1.6 | 0.047 | 0.18 |