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Figure 5 | BMC Genomics

Figure 5

From: Identification of tubular injury microRNA biomarkers in urine: comparison of next-generation sequencing and qPCR-based profiling platforms

Figure 5

Prediction of renal functions for miRNA from qPCR and NGS. (A) Analysis of the urinary miRNAs with altered expression in gentamicin induced tubular injury reveals significant correlations with renal injury. Black filled symbols represent miRNAs identified by qPCR as significantly changed in renal injury. White filled symbols are miRNAs identified as significantly changed by NGS and the gray filled symbols are the miRNAs identified as changed in both approaches. Note that Ingenuity’s software combines miRNAs with a common seed sequence to a single identifier. (B) Potential renal disease related mRNA targets for Let-7d, miR-203, and miR-320 identified by IPA are shown.

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BMC Genomics

ISSN: 1471-2164

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