Figure 10
From: Nucleosome organization in the vicinity of transcription factor binding sites in the human genome
Expression levels of target genes for each cluster of proximal activator and repressor binding sites. (A) Expression levels of target genes for each cluster of proximal activator binding sites in the GM12878 cell line. Genes associated with binding sites in Pattern 2 had significantly lower expression. (B) Expression levels of target genes for each cluster of proximal activator binding sites in the K562 cell line. Genes associated with sites in Pattern 3 had significantly lower expression. (C) Expression levels of target genes for each cluster of proximal repressor binding sites in the GM12878 cell line. Genes associated with proximal repressor sites in Pattern 3 had significantly lower expression. (D) Expression levels of target genes for each cluster of proximal repressor binding sites in the K562 cell line. Statistically significant differences were detected using a Wilcoxon rank-sum test.