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Figure 5 | BMC Genomics

Figure 5

From: Genome-wide identification of pathogenicity factors of the free-living amoeba Naegleria fowleri

Figure 5

Cellular component analysis of potential pathogenicity factors from N. fowleri. Gene Ontology (GO) graph generated from the cellular component ontology of the proteins, which were up-regulated in highly pathogenic trophozoites compared to weakly pathogenic trophozoites. The specificity of the GO terms increases from the bottom to the top of the graph with arrows indicating “being part of”. The majority of the potential pathogenicity factors localize to the membrane of the cell (blue marked circles), whereas another group of proteins localized to either cell projections (green marked circles) or vesicles (orange marked circles).

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