Table 6 Putative immunogenic enzymes in Amblyomma americanum tick saliva

GBAI01000009

BP6

FoF1 ATPase subunit6 Amblyomma americanum [ABA19091.1]

9^e-57

GBAJ01000009

BP10

F1F0 ATP-synthase subunit Cf6, putative Ixodes scapularis [XP_002399676.1]

8^e-55

GBAI01000048

BP6

7^e-46

GBAK01000355

BP13-14

vacuolar H + −ATPase V1 sector, subunit G, putative Ixodes scapularis [XP_002415521.1]

1^e-43

GBAK01000200

BP13-14

ADP/ATP translocase Ixodes scapularis [AAY66969.1]

9^e-19

GBAK01000110

BP13-14

inner mitochondrial membrane translocase TIM17-like protein, partial Ixodes scapularis [AAY66838.1]

5^e-40

GBAK01000320

BP13-14

mitochondrial malate dehydrogenase, partial Ixodes scapularis [AAY66975.1]

3^e-34

GBAI01000028

BP6

C1-tetrahydrofolate synthase, putative Ixodes scapularis [XP_002401635.1]

2^e-39

GBAK01000202

BP13-14

cytochrome oxidase subunit 1 Amblyomma americanum [ABA19092.1]

4^e-74

GBAL01000140

BP15-16

5^e-43

GBAI01000098

BP6

COX1 gene product (mitochondrion) Bothriocroton concolor [YP_006234392.1]

9^e-47

GBAI01000099

BP6

cytochrome c oxidase subunit I Rhipicephalus zambeziensis [AAG23880.1]

2^e-40

GBAK01000263

BP13-14

cytochrome c oxidase subunit I Amblyomma limbatum [ACM17834.1]

1^e-59

GBAL01000112

BP15-16

cytochrome oxidase subunit 1 Ixodes scapularis [ADO64507.1]

6^e-55

GBAL01000084

BP15-16

cytochrome c oxidase subunit I Rhipicephalus maculatus [AAG23878.1]

4^e-25

GBAL01000143

BP15-16

cytochrome oxidase subunit 2 Amblyomma americanum [ABA19093.1]

2^e-42

GBAK01000067

BP13-14

3^e-70

GBAK01000121

BP13-14

cytochrome oxidase subunit 3 Amblyomma americanum [ABA19094.1]

1^e-68

GBAL01000031

BP15-16

9^e-69

GBAK01000343

BP13-14

cytochrome c oxidase polypeptide IV Ixodes scapularis [AAY66918.1]

3^e-55

GBAK01000282

BP13-14

cytochrome c oxidase polypeptide Vb Ixodes scapularis [AAY66932.1]

2^e-37

GBAJ01000050

BP10

cytochrome C oxidase, subunit VIb/COX12, putative Ixodes scapularis [XP_002416556.1]

1^e-07

GBAK01000008

BP13-14

cytochrome oxidase subunit VIIc Ixodes pacificus [AAT92215.1]

2^e-32

GBAJ01000041

BP10

ubiquinol cytochrome c reductase subunit QCR7 Amblyomma variegatum [DAA34591.1]

7^e-52

GBAK01000326

BP13-14

4^e-47

GBAJ01000024

BP10

NADH:ubiquinone oxidoreductase, NDUFS2/49 kDa subunit, putative Ixodes scapularis [XP_002404495.1]

3^e-82

GBAJ01000104

BP10

NADH-ubiquinone oxidoreductase ashi subunit, putative Ixodes scapularis [XP_002409125.1]

2^e-08

GBAK01000386

BP13-14

estradiol 17-beta-dehydrogenase, putative Ixodes scapularis [XP_002434666.1]

5^e-33

GBAL01000014

BP15-16

NADH dehydrogenase subunit 1 (mitochondrion) Amblyomma cajennense [YP_007475022.1]

3^e-40

GBAK01000139

BP13-14

NADH dehydrogenase subunit 2 Amblyomma americanum [ABA19096.1]

3^e-10

GBAK01000133

BP13-14

NADH dehydrogenase subunit 3 (mitochondrion) Amblyomma cajennense [YP_007475021.1]

5^e-27

GBAL01000089

BP15-16

NADH dehydrogenase subunit 4 Amblyomma americanum [ABA19099.1]

3^e-33

GBAI01000088

BP6

alkyl hydroperoxide reductase, thiol specific antioxidant, putative Ixodes scapularis [XP_002405466.1]

2^e-42

thioredoxin peroxidase Ornithodoros parkeri [ABR23404.1]

1^e-41

GBAL01000174

BP15-16

peroxidase, putative Ixodes scapularis [XP_002404935.1]

1^e-34

GBAL01000029

BP15-16

thioredoxin reductase, putative Ixodes scapularis [XP_002404402.1]

1^e-68

GBAI01000050

BP6

putative glutathione S-transferase Dermacentor variabilis [ACF35539.1]

4^e-94

GBAK01000166

BP13-14

7^e-105

GBAL01000121

BP15-16

7^e-67

GBAL01000175

BP15-16

1^e-32

GBAK01000413

BP13-14

putative glutathione S-transferase Dermacentor variabilis [ACF35505.1]

9^e-32

GBAK01000042

BP13-14

gamma-glutamyltransferase, putative Ixodes scapularis [XP_002407102.1]

0.006

GBAL01000137

BP15-16

0.006

GBAL01000157

BP15-16

protein disulfide isomerase Amblyomma variegatum [ABD16189.1]

0

GBAK01000105

BP13-14

0

GBAK01000289

BP13-14

protein disulfide isomerase Amblyomma variegatum [DAA34067.1]

4^e-57

GBAI01000054

BP6

protein disulfide isomerase Haemaphysalis longicornis [ABS50238.1]

1^e-24

GBAI01000015

BP6

protein disulfide isomerase-1 Haemaphysalis longicornis [BAF63672.1]

9^e-04

GBAK01000337

BP13-14

protein disulfide isomerase-2 Haemaphysalis longicornis [BAF63671.1]

3^e-39

GBAI01000074

BP6

sulfotransferase, putative Ixodes scapularis [XP_002435996.1]

9^e-14

GBAJ01000030

BP10

3^e-19

GBAL01000144

BP15-16

0.033

GBAJ01000034

BP10

sulfotransferase, putative Ixodes scapularis [XP_002436296.1]

7^e-14

GBAL01000136

BP15-16

sulfotransferase, putative Ixodes scapularis [XP_002400534.1]

3^e-35

GBAK01000319

BP13-14

glycosyl transferase, putative Ixodes scapularis [XP_002434372.1]

2^e-31

GBAK01000388

BP13-14

1^e-38

GBAK01000266

BP13-14

acyl-CoA synthetase, putative Ixodes scapularis [XP_002401840.1]

2^e-31

GBAK01000079

BP13-14

adenylosuccinate lyase, putative Ixodes scapularis [XP_002399354.1]

4^e-34

GBAK01000191

BP13-14

casein kinase, putative Ixodes scapularis [XP_002400161.1]

2^e-30

GBAL01000108

BP15-16

1^e-30

GBAK01000072

BP13-14

3-hydroxyacyl-CoA dehydrogenase, putative Ixodes scapularis [XP_002415080.1]

1^e-79

GBAI01000093

BP6

malonyl CoA-acyl carrier protein transacylase, putative Ixodes scapularis [XP_002402213.1]

5^e-15

GBAI01000059

BP6

dihydrolipoamide acetyltransferase, putative Ixodes scapularis [XP_002401656.1]

8^e-05

GBAJ01000090

BP10

RAB GTPase-activating protein, putative Ixodes scapularis [XP_002407414.1]

2^e-29

GTPase-activating protein Amblyomma variegatum [DAA34545.1]

3^e-27

GBAK01000234

BP13-14

ubiquitin protein ligase Ixodes scapularis [XP_002434331.1]

2^e-28

GBAI01000014

BP6

SCF ubiquitin ligase Skp1 component Amblyomma variegatum [DAA34559.1]

2^e-46

SCF ubiquitin ligase complex Ixodes scapularis [AAY66893.1]

2^e-46

GBAK01000329

BP13-14

phosphoribosylformylglycinamidine synthase, putative Ixodes scapularis [XP_002405859.1]

2^e-35

GBAK01000254

BP13-14

lysine-ketoglutarate reductase/saccharopine dehydrogenase Haemaphysalis longicornis [BAI44335.1]

6^e-77

lysine-ketoglutarate reductase, putative Ixodes scapularis [XP_002404033.1]

3^e-70

GBAK01000268

BP13-14

pterin-4-alpha-carbinolamine dehydratase, putative Ixodes scapularis [XP_002399841.1]

1^e-56

GBAK01000157

BP13-14

ornithine aminotransferase, putative Ixodes scapularis [XP_002406120.1]

2^e-45

GBAI01000082

BP6

methionyl-tRNA synthetase, putative Ixodes scapularis [XP_002433760.1]

6^e-32

GBAK01000365

BP13-14

aspartyl-tRNA synthetase, putative Ixodes scapularis [XP_002404413.1]

6^e-39

GBAL01000251

BP15-16

cysteine synthase, putative Ixodes scapularis [XP_002415219.1]

3^e-39

GBAL01000103

BP15-16

ng,ng-dimethylarginine dimethylaminohydrolase, putative, mRNA Ixodes scapularis [XM_002404864.1]

1^e-05

GBAL01000038

BP15-16

keratinocyte transglutaminase, putative Ixodes scapularis [XP_002402412.1]

3^e-46

GBAK01000354

BP13-14

2^e-36

GBAK01000325

BP13-14

lysosomal acid phosphatase Haemaphysalis longicornis [ADN34299.1]

9^e-66

GBAJ01000044

BP10

triosephosphate isomerase Rhipicephalus microplus [AFP81689.1]

8^e-103

GBAL01000080

BP15-16

phosphoenolpyruvate carboxykinase Rhipicephalus microplus [ABO61883.1]

2^e-36

phosphoenolpyruvate carboxykinase, putative Ixodes scapularis [XP_002404833.1]

1^e-32

GBAK01000024

BP13-14

D-dopachrome tautomerase, putative Ixodes scapularis [XP_002401879.1]

2^e-10

GBAJ01000109

BP10

transposase, putative Ixodes scapularis [XP_002415790.1]

8^e-19

GBAI01000002

BP6

ribosomal protein S6 kinase, putative Ixodes scapularis [XP_002405308.1]

3^e-21