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Table 2 Regions of Genomic Plasticity (RGPs) identified in the K. pneumoniae Kp13 chromosome

From: Comparative analysis of the complete genome of KPC-2-producing Klebsiella pneumoniae Kp13 reveals remarkable genome plasticity and a wide repertoire of virulence and resistance mechanisms

Region Coordinates Length (kbp) No. of CDSs G + C% Features Best hit (% coverage, e-value)*
RGP1 748,751 – 764,155 15.4 17 59% s.b.; dGC%; transposases K. pneumoniae MGH 78578 (100%, 0.0)
RGP2 1,031,543 – 1,043,427 11.9 9 37% s.b.; dGC%; phage; transposases Enterobacter cloacae ATCC 13047 (10%, 0.0)
RGP3 1,294,343 – 1,335,472 41.1 55 52% s.b.; dGC%; phage Escherichia coli IHE3034 (23%, 0.0)
RGP4 1,444,954 – 1,481,531 36.6 36 50% s.b.; dGC%; T6SS; tRNA; transposases Salmonella enterica (55 %, 0.0)
RGP5 1,827,686 – 1,893,227 65.5 59 53% s.b.; tRNA; dGC%; T4SS Enterobacter hormaechei (93%, 0.0)
RGP6 2,056,825 – 2,088,335 31.5 35 52% s.b.; T6SS; dGC%; transposases K. pneumoniae NTUH-K2044 (85%, 0.0)
RGP7 2,278,838 – 2,293,758 14.9 17 46% s.b.; dGC%; transposases K. pneumoniae HS11286 (91%, 0.0)
RGP8 2,961,023 – 2,987,614 26.6 20 60% s.b.; T6SS; dGC% K. pneumoniae KCTC 2242 (98%, 0.0)
RGP9 3,155,750 – 3,244,119 88.4 111 52% s.b.; dGC%; phage K. pneumoniae MGH 78578 (29%, 0.0)
RGP10 3,425,935 – 3,436,504 10.6 9 48% s.b.; dGC%; transposases K. pneumoniae MGH 78578 (75%, 0.0)
RGP11 3,898,258 – 3,906,459 8.2 9 54% s.b.; transposases K. pneumoniae MGH 78578 (100%, 0.0)
RGP12 4,204,889 – 4,234,405 29.5 33 48% s.b.; dGC%; tRNA; transposases K. pneumoniae KCTC 2242 (43%, 0.0)
RGP13 4,660,071 – 4,695,371 35.3 32 50% s.b.; dGC%; tRNA; transposases K. pneumoniae KCTC 2242 (60%, 0.0)
  1. *BLASTN performed against the ‘nr’ database at the NCBI website; dGC%, deviation from mean chromosomal GC content; s.b., synteny break from at least one other compared K. pneumoniae; phage, probable bacteriophage region; tRNA, presence of flanking transfer RNAs; transposases, presence of transposase-related sequences; T4SS/T6SS, presence of, respectively, types IV/VI secretion systems.