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Table 3 Characteristics of the beta-lactamases identified in the Kp13 genome

From: Comparative analysis of the complete genome of KPC-2-producing Klebsiella pneumoniae Kp13 reveals remarkable genome plasticity and a wide repertoire of virulence and resistance mechanisms

Product Gene CDS Genetic element Best hit (% identity*, isolation country)
Beta-lactamase SHV-12 bla SHV12 KP32248 pKP13f K. pneumoniae MGH 78578 (100%, USA)
Beta-lactamase OXA-9 bla OXA9 KP01389 pKP13f K. pneumoniae FC1 (100%, Argentine)
Beta-lactamase TEM-1 bla TEM-1 KP01391 pKP13f Neisseria gonorrhoeae (100%, nd)
Beta-lactamase CTX-M-2 bla CTX-M-2 KP03128 pKP13f Salmonella typhimurium CAS-5 (100%, Argentine)
Beta-lactamase SHV-110 bla SHV110 KP31849 Chr K. pneumoniae FSP 237/05 (100%, Brazil)
Beta-lactamase KPC-2 bla KPC-2 KP06703 pKP13d K. pneumoniae 15 (100%, USA)
  1. *,BLASTP against the NCBI database; Chr, chromosome; nd, not determined; pKP13[d/f], plasmid pKP13d/pKP13f.