Table 1 TRKOs those are unable to grow on YP-Glycerol and their mutant phenotypes
ORF | Gene | Description | Mutant phenotype |
|---|---|---|---|
orf19.4853 | HCM1 | Has a forkhead domain; involved in hyphal morphogenesis; similar to the S.cerevisiae ortholog that regulates transcription during S-phase of the mitotic cell cycle | Vegetative growth decreased in YPG |
orf19.7068 | MAC1 | Regulon of CaCTR 1, a high affinity copper transporter gene; role in ion homeostasis | Vegetative growth decreased in YPG |
orf19.2088 | DPB4 | Putative DNA polymerase epsilon subunit D; Ortholog of S.cerevisiae involved in DNA-dependent DNA replication | Viable, slow-growing and displays abnormal invasive growth |
orf19.3063 | HFL1 | HAP5-like; phosphorylated protein | Vegetative growth decreased in YPG |
orf19.5558 | RBF1 | Glutamine-rich activation domain; binds RPG-box DNA sequences; antigenic during human oral infection | Vegetative growth decreased in YPG |
orf19.6109 | TUP1 | Co-repressor; represses filamentous growth; regulates switching | Abnormal colony appearance on YPD and YPG |