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Table 2 Antifungal drug susceptibilities to cell membrane and cell wall inhibitors*

From: The Rbf1, Hfl1 and Dbp4 of Candida albicans regulate common as well as transcription factor-specific mitochondrial and other cell activities

Gene KO

Fluconazole(μg/ml)

AmB (μg/ml)

Caspofungin (μg/ml)

MIC100

MIC50

MIC100

MIC100

WT

256

0.5

0.25

0.25

GOA1

1.0

1.0

1.0

0.0625

DPB4

256

1.0

1.0

0.5

HFL1

2.0

0.25

0.5

0.125

RBF1

2.0

0.25

0.25

0.0625

  1. *Data reflect averages of 3 experiments.