Table 2 Analysis of biological functions induced infection of human monocyte-derived macrophages with M. avium isolates
Biological functions | Enrichment score | |
|---|---|---|
Mah VI101 compared to uninfected | Negative regulation of apoptosis | 15.2 |
Inflammatory response | 13.5 | |
Induction of apoptosis | 12.7 | |
Cytokine/chemokine activity | 8.4 | |
Regulation of cytokine production | 7.1 | |
Regulation of signal transduction | 6.6 | |
Regulation of T and B cell activation/proliferation | 6.0 | |
Regulation of protein cytokine secretion | 5.2 | |
Regulation of phosphorylation | 4.8 | |
Response to molecule of bacterial origin | 3.8 | |
Mah 1655 compared to uninfected | Inflammatory response | 15.5 |
Negative regulation of apoptosis | 9.8 | |
Induction of apoptosis | 6.6 | |
Cytokine/chemokine activity | 5.9 | |
Regulation of T and B cell activation/proliferation | 4.5 | |
Regulation of phosphorylation | 4.2 | |
Response to molecule of bacterial origin | 4.1 | |
Regulation of viral replication | 3.6 | |
Pattern recognition receptor pathway signalling | 3.5 | |
Cell migration | 3.5 | |
Maa 1794 compared to uninfected | Inflammatory response | 16.5 |
Negative regulation of apoptosis | 14.2 | |
Induction of apoptosis | 13.0 | |
Response to molecule of bacterial origin | 8.3 | |
Regulation of signal transduction | 8.2 | |
Cytokine/chemokine activity | 7.6 | |
Regulation of T and B cell activation/proliferation | 6.6 | |
Regulation of cytokine production | 6.0 | |
Regulation of protein cytokine secretion | 4.9 | |
Regulation of phosphorylation | 4.3 |