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Table 3 Ingenuity pathway analysis of enriched pathways during different repair phases

From: Micro-RNAs in regenerating lungs: an integrative systems biology analysis of murine influenza pneumonia

Day 7 networks

Score

Hematological system development and function, Tissue morphology, Cellular development

52

Antimicrobial response, Inflammatory response, Infectious Disease

40

Cell-to-cell signaling and interaction, Cellular growth and proliferation, Hematological system development and function

37

Cardiovascular system development and function, Cell morphology, Hematological system development and function

31

Cell-to-cell signaling and interaction, Cellular function and maintenance, Hematological system development and function

31

Day 15 networks

Score

Nucleic acid metabolism, Small molecule biochemistry, Cellular development

42

Cell-to-cell signaling and interaction, Cell signaling, Nucleic acid metabolism

40

DNA replication, recombination, and repair, Cell cycle, Cellular assembly and organization

36

Cell death and survival, Cell-to cell signaling and interaction, Hematological system development and function

35

Cellular compromise, DNA replication, recombination and repair, Energy production

35

  1. Note: IPA analysis based on gene function enrichment. Enrichment score is a modified P-value and indicates the likelihood of the Focus Genes in a network being found together due to random chance. A score of 2 denotes that there is a 1-in-100 chance that the Focus Genes are together in a network due to random chance. Therefore, scores of 2 or higher have at least 99% confidence of not being generated by random chance alone.
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BMC Genomics

ISSN: 1471-2164

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