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Table 3 Signaling pathways associated with differentially expressed genes

From: Gene expression profiling of mesenteric lymph nodes from sheep with natural scrapie

Term P value ProbeName FC (C vs NC) FC (PC vs NC) Gene symbol Gene name
PPAR signaling pathway 1.88E-02 CUST_598_PI375351158 2.28 1.33 FABP5 Fatty acid binding protein 5 (psoriasis-associated)
CUST_8730_PI375351158 1.06 −2.05 ACSL4 Acyl-CoA synthetase long-chain family member 4
A_70_P058551 8.25 −1.12 FABP4 Fatty acid binding protein 4, adipocyte
A_70_P039986 −1.27 2.39 SLC27A2 Solute carrier family 27 (fatty acid transporter), member 2
ECM-receptor interaction 2.53E-02 A_70_P021711 −2.19 −1.69 COL1A1 Collagen, type I, alpha 1
A_70_P058626 2.27 1.13 VWF von Willebrand factor
A_70_P016337 −1.78 −2.72 HMMR Hyaluronan-mediated motility receptor (RHAMM)
Focal adhesion 6.73E-02 A_70_P021711 −2.19 −1.69 COL1A1 Collagen, type I, alpha 1
A_70_P058626 2.27 1.13 VWF von Willebrand factor
A_70_P050922 2.19 −1.06 VEGFA Vascular endothelial growth factor A
A_70_P031441 −2.43 −1.79 VCL Vinculin
  1. Signaling pathways with which differentially expressed genes (P ≤ 0.05 and ≥ 2-fold change) are associated were identified by enrichment analysis using the on-line functional annotation (DAVID Bioinformatics Resources 6.7; NIAID/NIH, USA). (C, Clinical; FC, Fold change; NC, Negative control; PC, Preclinical).