Figure 4

The core trichothecene clusters of Stachybotrys, Trichoderma, and F. graminearum, and satratoxin chemotype-specific clusters SC1, SC2, and SC3 of Stachybotrys. A. The core trichothecene cluster (CTC). For all genomes an arrow indicates a gene and its transcriptional sense. The core trichothecene clusters of Stachybotrys are shown in the green box, and the adjacent satratoxin cluster SC3 is shown in the pink box. The other genes that are shown outside the boxes lack similarity to known trichothecene synthesis genes, so they are assumed to be in flanking regions outside these two clusters. A black, dotted arrow indicates that a scaffold extends to include other genes beyond the region shown, whereas lack of such an arrow indicates a scaffold border. The color indicates orthology with respect to Trichoderma and F. graminearum trichothecene clusters (shown in the gray, dotted box). TRI18, which is a paralog of TRI3, is colored as TRI3, but the arrow is dotted. Note that Trichoderma TRI5 is known to exist outside of the CTC [12]. The ruler at the top indicates length in kbp. Trichoderma and F. graminearum CTCs were redrawn from prior work [12, 29]. B. The satratoxin-specific clusters are shown in the pink boxes. The other genes shown are chemotype-independent. Other figure conventions follow those described for the CTC.