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Table 1 Kyoto Encyclopedia of Genes and Genomes (KEGG) terms associated with transcripts that had significant differential expression in response to RDX exposure compared to controls in a 5d experiment

From: Coral-zooxanthellae meta-transcriptomics reveals integrated response to pollutant stress

0.5 mg/L RDX

Cor

Alg

Oth

1.8 mg/L RDX (cont.)

Cor

Alg

Oth

7.2 mg/L RDX (cont.)

Cor

Alg

Oth

1. Metabolism

14

0

0

Pyruvate metabolism

0

0

1

1.4 Nucleotide Metabolism

1

1

0

 1.1 Carbohydrate Metabolism

5

0

0

Glyoxylate and dicarboxylate metabolism

1

0

0

Purine metabolism

1

1

0

  Glycolysis/Gluconeogenesis

1

0

0

Butanoate metabolism

0

0

1

1.5 Amino Acid Metabolism

4

0

3

  Citrate cycle (TCA cycle)

2

0

0

1.2 Energy Metabolism

2

1

0

Alanine and aspartate metabolism

0

0

1

  Pyruvate metabolism

2

0

0

Oxidative phosphorylation

2

1

0

Glycine, serine and threonine metabolism

2

0

1

 1.2 Energy Metabolism

1

0

0

1.3 Lipid Metabolism

0

0

3

Valine, leucine and isoleucine biosynthesis

1

0

1

  Nitrogen metabolism

1

0

0

Fatty acid metabolism

0

0

1

Lysine degradation

1

0

0

 1.3 Lipid Metabolism

2

0

0

Bile acid biosynthesis

0

0

1

1.6 Metabolism of Other Amino Acids

2

0

0

  Fatty acid metabolism

1

0

0

Glycerolipid metabolism

0

0

1

Cyanoamino acid metabolism

1

0

0

  Arachidonic acid metabolism

1

0

0

1.5 Amino Acid Metabolism

3

0

3

Glutathione metabolism

1

0

0

 1.4 Nucleotide Metabolism

1

0

0

Glutamate metabolism

2

0

0

1.9 Metabolism of Cofactors and Vitamins

7

1

0

  Purine metabolism

1

0

0

Alanine and aspartate metabolism

0

0

1

One carbon pool by folate

1

0

0

 1.5 Amino Acid Metabolism

1

0

0

Glycine, serine and threonine metabolism

0

0

1

Porphyrin and chlorophyll metabolism

0

1

0

  Glutamate metabolism

1

0

0

Valine, leucine and isoleucine biosynthesis

0

0

1

Limonene and pinene degradation

1

0

0

 1.6 Metabolism of Other Amino Acids

2

0

0

Arginine and proline metabolism

1

0

0

Phenylpropanoid biosynthesis

1

0

0

  Glutathione metabolism

2

0

0

1.6 Metabolism of Other Amino Acids

1

0

0

Streptomycin biosynthesis

1

0

0

 1.7 Glycan Biosynthesis and Metabolism

2

0

0

Glutathione metabolism

1

0

0

Gamma-Hexachlorocyclohexane degradation

1

0

0

  Chondroitin sulfate biosynthesis

1

0

0

    

Naphthalene and anthracene degradation

1

0

0

  Glycan structures - biosynthesis 1

1

0

0

2. Genetic Information Processing

1

0

1

Fluorene degradation

1

0

0

    

2.1 Transcription

0

0

1

    

3. Environmental Information Processing

4

0

0

Aminoacyl-tRNA biosynthesis

0

0

1

2. Genetic Information Processing

3

0

2

 3.1 Membrane Transport

1

0

0

2.3 Folding, Sorting and Degradation

1

0

0

2.1 Transcription

1

0

1

  ABC transporters - General

1

0

0

Protein export

1

0

0

Aminoacyl-tRNA biosynthesis

1

0

1

 3.2 Signal Transduction

3

0

0

    

2.2 Translation

2

0

1

  MAPK signaling pathway

1

0

0

3. Environmental Information Processing

1

1

0

Ribosome

2

0

1

  ErbB signaling pathway

1

0

0

3.2 Signal Transduction

1

1

0

    

  Wnt signaling pathway

1

0

0

Two-component system - General

0

1

0

3. Environmental Information Processing

9

1

0

    

Wnt signaling pathway

1

0

0

3.1 Membrane Transport

1

0

0

4. Cellular Processes

6

0

0

    

ABC transporters - General

1

0

0

 4.2 Cell Growth and Death

1

0

0

4. Cellular Processes

2

0

0

3.2 Signal Transduction

8

1

0

  Cell cycle

1

0

0

4.3 Cell Communication

1

0

0

Two-component system - General

0

1

0

 4.3 Cell Communication

1

0

0

Adherens junction

1

0

0

MAPK signaling pathway

2

0

0

  Focal adhesion

1

0

0

Tight junction

1

0

0

ErbB signaling pathway

1

0

0

 4.4 Endocrine System

1

0

0

    

Wnt signaling pathway

1

0

0

  GnRH signaling pathway

1

0

0

7.2 mg/L RDX

Cor

Alg

Oth

VEGF signaling pathway

1

0

0

 4.5 Immune System

3

0

0

1. Metabolism

26

7

8

Calcium signaling pathway

1

0

0

  Toll-like receptor signaling pathway

1

0

0

1.1 Carbohydrate Metabolism

6

3

3

Phosphatidylinositol signaling system

2

0

0

  T cell receptor signaling pathway

1

0

0

Glycolysis/Gluconeogenesis

1

2

1

    

  B cell receptor signaling pathway

1

0

0

Pentose and glucuronate interconversions

1

0

0

4. Cellular Processes

6

0

0

    

Ascorbate and aldarate metabolism

1

0

0

4.3 Cell Communication

3

0

0

5. Human Diseases

2

0

0

Starch and sucrose metabolism

1

0

0

Focal adhesion

2

0

0

 5.1 Cancers

2

0

0

Nucleotide sugars metabolism

1

0

0

Tight junction

1

0

0

  Colorectal cancer

1

0

0

Pyruvate metabolism

0

1

1

4.4 Endocrine System

1

0

0

  Renal cell carcinoma

1

0

0

Butanoate metabolism

0

0

1

Melanogenesis

1

0

0

    

Inositol phosphate metabolism

1

0

0

4.5 Immune System

1

0

0

1.8 mg/L RDX

Cor

Alg

Oth

1.2 Energy Metabolism

4

2

1

Natural killer cell mediated cytotoxicity

1

0

0

1. Metabolism

13

1

10

Oxidative phosphorylation

2

0

1

4.6 Nervous System

1

0

0

 1.1 Carbohydrate Metabolism

7

0

4

Photosynthesis

0

1

0

Long-term potentiation

1

0

0

  Glycolysis/Gluconeogenesis

0

0

2

Carbon fixation

0

1

0

    

  Citrate cycle (TCA cycle)

1

0

0

Methane metabolism

1

0

0

5. Human Diseases

1

0

0

  Pentose phosphate pathway

1

0

0

Nitrogen metabolism

1

0

0

5.1 Cancers

1

0

0

  Pentose and glucuronate interconversions

1

0

0

1.3 Lipid Metabolism

2

0

1

Glioma

1

0

0

  Ascorbate and aldarate metabolism

1

0

0

Fatty acid metabolism

0

0

1

    

  Starch and sucrose metabolism

1

0

0

Glycerophospholipid metabolism

1

0

0

    

  Nucleotide sugars metabolism

1

0

0

Arachidonic acid metabolism

1

0

0

    
  1. KEGG terms are matched to source sequences: Coral (Cor), Algal Symbionts (Alg), or other (Oth) for non-specific phylogenetic associations.