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Table 2 Commonly over-expressed genes in both datasets

From: Gene network-based analysis identifies two potential subtypes of small intestinal neuroendocrine tumors

Concurrent analysis*

Symbol

Name

Process/function

SCG5

Secretogranin V (7B2 protein)

Transport/Enzyme inhibitor activity

PCSK1

Proprotein convertase subtilisin/kexin type 1

Energy reserve metabolic process/Endopeptidase activity

SCN3A

Sodium channel, voltage-gated, type III, alpha subunit

Ion transport/Voltage-gated ion channel activity

PNMA2

Paraneoplastic Ma antigen 2

Apoptotic process/Protein binding

NKX2-2

NK2 homeobox 2

Type B pancreatic cell development/Core promoter proximal region DNA binding

SCG2

Secretogranin II

MAPK cascade/Cytokine activity

ST18

Suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)

Negative regulation of transcription from RNA polymerase II promoter/DNA binding

INSM1

Insulinoma-associated 1

Regulation of transcription, DNA-dependent/DNA binding

CPE

Carboxypeptidase E

Cardiac left ventricle morphogenesis/Carboxypeptidase activity

BEX1

Brain expressed, X-linked 1

Multicellular organismal development/RNA polymerase II activating transcription factor binding

APLP1

Amyloid beta (A4) precursor-like protein 1

MRNA polyadenylation/Protein binding

AKT3

V-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

Mitochondrial genome maintenance/Nucleotide binding

CD59

CD59 molecule, complement regulatory protein

Cell surface receptor signaling pathway/Protein binding

  1. *This manuscript.