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Figure 5 | BMC Genomics

Figure 5

From: Bis-class: a new classification tool of methylation status using bayes classifier and local methylation information

Figure 5

The GB 16479 locus exhibits qualitatively identical information yet opposite methylation calling under the binomial method. Data are from unpublished methylC-seq experiments of two honey bee individuals from the Yi lab, and are available upon request. All reads mapped to the four CpGs are ‘C’ reads (indicating 100% methylation). However, the binomial method provides a different methylation calls for these two samples. Specifically, the binomial calls all CpGs in the sample A as non-methylated (white dots), and all CpGs in the sample B as methylated (black dots). Bis-Class correctly identifies identical methylation features in the two replicates.

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