Figure 3
From: A nonsense mutation in PLD4 is associated with a zinc deficiency-like syndrome in Fleckvieh cattle
Mapping of the locus for a zinc deficiency-like syndrome in the Fleckvieh population. Association of 644,450 SNPs with the affection status of eight affected and 1,339 unaffected Fleckvieh animals (A). P values were obtained by fitting a linear mixed model. Autozygosity mapping in eight affected calves and one unaffected animal (B). Blue and pale blue represent homozygous genotypes (AA and BB), heterozygous genotypes (AB) are displayed in light grey. The red bar indicates the common segment of homozygosity. Note that one unaffected animal is also homozygous for the segment of extended homozygosity. The segment of extended homozygosity encompasses 17 transcripts/genes among them CRIP1, CRIP2 and PLD4 (C).