Phylogeny of CMGC kinases and HSP90. (A) Phylogeny of CDKs, showing the placement of previously identified cell-cycle kinases in O. tauri into the topology of a CMGC phylogeny. (B) Phylogeny of GSK3, highlighting the closer proximity of O. tauri and A. thaliana to the H. sapiens sequences (relative to S. cerevisiae). (C) Phylogeny of HSP90 chaperone, showing a similar topology to GSK3. (D) Phylogeny of MAPK, showing specialisation of A. thaliana MAPKs into two clades. A general explanation for phylogenies is in Figure 2. In (C) all omitted bootstrap values are 100%. Dashed arrows (red) show the distance (sum of branch lengths) from the nearest A. thaliana, S. cerevisiae and O. tauri sequence to the point at which H. sapiens sequences diverge, in B-D.