Figure 8
Phylogenies CK1, CK2α and CK2β. (A) Phylogeny of CK1, revealing an O. tauri ortholog in close proximity H. sapiens (relative to A. thaliana and S. cerevisiae). (B) Phylogeny of CK2α catalytic subunit showing the closer proximity of A. thaliana CK2α to the H. sapiens sequences (relative to S. cerevisiae). (C) Phylogeny of CK2β regulatory subunit, revealing a similar topology and rate of relative divergence to the CK2α subunit. A general explanation for phylogenies is in Figure 2. Raw branch lengths (red) are annotated to broken-line arrows and show distances from O. tauri, A. thaliana, and S. cerevisiae to the H. sapiens and D. melanogaster divergence point. For (B) the H. sapiens CK1γ isoforms are not shown, as they are more divergent than the other sequences included. The CK2α2 branch has been truncated as it was considerably more divergent than CK2α1. S. cerevisiae identifiers are standard names from SGD. Accessions for D. melanogaster and H. sapiens proteins are given in Additional file 9: Table S3.