Figure 2
From: Prediction of miRNA-mRNA associations in Alzheimer’s disease mice using network topology
The subnetwork of weighted coexpression networks of miRNA-mRNA in AD. (A) The subnetwork of brown, grey, and pink module genes and related miRNAs. As presented in Figure 1 transgenic plots (left), these 3 modules show negative correlations. (B) The subnetwork of green (cor = 0.64) and yellow (cor = 0.69) module genes and related miRNAs. (C) The subnetwork of weighted coexpression networks. A compact network was constructed from arrestin domain containing 3 (ARRDC3) neighbors and related miRNAs to their target genes. The interaction between miRNA and their target genes were predicted by sequence analysis and expression anti-correlation.