Figure 2
From: Genome-wide DNA methylation changes in skeletal muscle between young and middle-aged pigs
Comparison of the methylation state between young and MA pigs across chromosomes. Methylation levels in (A) subtelomeric versus non-subtelomeric regions and (B) the subtelomeric regions of young versus middle-aged pigs on each chromosome. Student’s t-test revealed no significant difference between the two groups. (C) Distribution of DNA methylation on pig chromosome 12. (D) Top: the average DNA methylation in subtelomeric regions in young versus middle-aged pigs. The significance was evaluated using a paired samples t-test (P = 4.92 × 10−7). Bottom: the T/S ratio (telomere signal versus the signal of the single-copy gene) reflects the relative telomere length in young and middle-aged pigs.