Figure 3
From: Genome-wide DNA methylation changes in skeletal muscle between young and middle-aged pigs
Genome-wide distribution of differentially methylated regions. The x-axis denotes the percentage of CpG sites within DMRs in each of 24 genomic elements (number of CpGs in DMRs versus the total number of CpGs in each of the genomic features). (A) Promoters were classified into nine categories based on their CpG representation (HCP, ICP and LCP) and genomic location (D, I, P). The significance of the pairwise comparisons among HCPs, ICPs and LCPs was evaluated using t-tests, whereas the CpG percentage showed no significant difference among the D, I and P promoters. (B) CpG percentages in various gene structures. (C) Comparison of CpG percentages between CGIs and CGI shores located in distinct genomic regions. The significance of the comparison of CpG percentages between CGIs and CGI shores was evaluated using two-way ANOVA.