TY - JOUR AU - Ji, Ting AU - Liu, Zhenguo AU - Shen, Jie AU - Shen, Fang AU - Liang, Qin AU - Wu, Liming AU - Chen, Guohong AU - Corona, Miguel PY - 2014 DA - 2014/08/08 TI - Proteomics analysis reveals protein expression differences for hypopharyngeal gland activity in the honeybee, Apis mellifera carnica Pollmann JO - BMC Genomics SP - 665 VL - 15 IS - 1 AB - Most of the proteins contained in royal jelly (RJ) are secreted from the hypopharyngeal glands (HG) of young bees. Although generic protein composition of RJ has been investigated, little is known about how age-dependent changes on HG secretion affect RJ composition and their biological consequences. In this study, we identified differentially expressed proteins (DEPs) during HG development by using the isobaric tag for relative and absolute quantification (iTRAQ) labeling technique. This proteomic method increases the potential for new protein discovery by improving the identification of low quantity proteins. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-15-665 DO - 10.1186/1471-2164-15-665 ID - Ji2014 ER -