Distributions of motifs around TSSs. Horizontal axes represent sequence areas from -1000 to +1000 from TSSs. Vertical axes represent the ratio of motif frequencies and theoretical frequencies (see Methods). (A) Distributions of the ATGGGG motif; (B) Distribution of the CCCCAT motif; (C) Distributions of the ACACA (blue), TGTGT (red), and TATAT (green) motifs; (D) Distributions of the other 5-mer motifs; (E) Distributions of the ACACA (blue), TGTGT (red), and TATAT (green) motifs in humans; (F) Distributions of all 5-mer repeat combinations in humans; (G) Distributions of the known apicomplexan motifs GATTCC, GCATGC, GTGCAC, and TAGCTA and the core mammalian promoter motifs TATA, TATAWAAR; BREu, SSRCGCC; BREd, RTDKKKK; and the DPE, RGWYVT. In A, B, and G, the scanning window was 10 bp. In C–F the scanning window was 30 bp.