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Table 3 DNA replication proteins compared to the corresponding components in Thermoplasmatales, MG-II and DHEV2

From: Comparative genomics highlights the unique biology of Methanomassiliicoccales, a Thermoplasmatales-related seventh order of methanogenic archaea that encodes pyrrolysine

  "Ca. M. alvus" "Ca. M. intestinalis" M. luminyensis MG-II DHEV2 Thermoplasmatales
ATP-dependent DNA ligase AGI85913 AGN25909 WP_019176428 X
Orc1/Cdc6 AGI84758 (1) AGN25419 (1) WP_019178385 (1) ■■ ■■
AGI85775 (2) AGN27158 (2) WP_019178317 (2)
DNA Pol D large subunit (DPL) AGI85099 AGN26720 WP_019177373
DNA Pol D small subunit (DPS) AGI84772 AGN27082 WP_019178373
FEN-1 AGI85207 AGN26626 WP_019176843
GINS 51 AGI84890 AGN27100 X X
GINS 23 X X X X X X
DNA Gyrase subunit B [AGI86382] [AGY50228] [WP_019178436] [■] [■] [■]
DNA Gyrase subunit A [AGI86381] [AGN27159] [WP_019178437] [■] [■] [■]
MCM AGI86392 AGN26346 WP_019178416
AGN27203
PCNA AGI84935 AGN27068 WP_019176118
DNA Pol B AGI86264 AGN26701 WP_019177962
WP_019177491
Primase large subunit (PriL) AGI84820 AGN27177 WP_019178297
Primase small subunit (PriS) AGI86400 AGY50234 WP_019178400
RFC large subunit AGI85559 AGN26596 WP_019176873
RFC small subunit AGI85778 AGN26166 WP_019177244
RNaseH II AGI86158 AGN25790 WP_019177553
TopoVI subunit A AGI85998 AGN26743 WP_019177592 X
TopoVI subunit B AGI85997 AGN26742 WP_019177591 X
Topo IB X X X X X X
SSB X X X X
RPA2 AGI84916 AGN25568 WP_019178149
AGY50184 WP_019177069
rpa2A (rp associated protein) AGI84915 AGN25567 WP_019178150
NAD-dependent DNA ligase [AGI85455] X X [■] X X
  1. Proteins in brackets indicate horizontal transfers from bacteria; Proteins in italics indicate fast evolving additional copies likely representing decaying paralogs, genes horizontally transferred among archaea, or homologs arising from integration of foreign elements. Absent proteins (or unavailable due to genome incompleteness) are indicated by an X. (1) and (2) in front of the Orc1/Cdc6 protein accession numbers indicate the Orc1/Cdc6.1 and Orc1/Cdc6.2, respectively.