Figure 5
From: Relating gene expression evolution with CpG content changes
Relationship between gene expression change and nCpG difference between human and mouse. The increase of average expression change, log2(hsa/mmu), is accompanied with the increase of nCpG difference (dCpG) of TSS (A) and TTS (B). Consistently, genes highly expressed in human (>two-fold change) have significantly larger nCpG difference (human versus mouse) in their TSS (C) and TTS (D) proximal DNA regions than those lowly expressed genes.