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Table 1 Deregulated oncogenic or tumour suppressive miRNAs in 2102Ep and NTera-2 cells with an upregulated or downregulated profile in undifferentiated or differentiated hESC data from Stadler et al.[45]

From: An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines

2102Ep hESC undifferentiated hESC differentiated
OncomiR Downregulated miR-519c Upregulated Downregualted
miR-19a miR-519d miR-24 miR-26a
miR-512-5p miR-520a*   miR-31
miR-517a miR-520b   miR-125b
miR-517b miR-520f   mir-182
miR-517c miR-520 g   miR-221
miR-518b miR-520 h   
miR-518f    
miR-525    
Tumour Suppressor miRNA Downregulated Upregulated Downregulated
miR-148a miR-424 miR-26a
  miR-27b miR-31
miR-28 miR-125b
miR-30d  
miR-149  
miR-331  
NTera-2 hESC undifferentiated hESC differentiated
OncomiR Downregulated Upregulated Downregulated
miR-18a miR-193b miR-22
miR-19a   miR-125b
miR-19b   miR-221
miR-367   miR-222
miR-374   
miR-517c   
Tumour Suppressor miRNA   Upregulated Downregulated
miR-145 miR-22
miR-193b miR-31
  miR-125b
  miR-34c
  1. The individual titles ‘Downregulated’ and ‘Upregulated’ indicate the differential expression of each miRNA after SOX2 knock-down in either 2102Ep or NTera-2 cell lines or both.