BMC Genomics

Table 1 Deregulated oncogenic or tumour suppressive miRNAs in 2102Ep and NTera-2 cells with an upregulated or downregulated profile in undifferentiated or differentiated hESC data from Stadler et al.[45]

From: An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines

2102Ep	hESC undifferentiated		hESC differentiated
OncomiR	Downregulated	miR-519c	Upregulated	Downregualted
	miR-19a	miR-519d	miR-24	miR-26a
	miR-512-5p	miR-520a*		miR-31
	miR-517a	miR-520b		miR-125b
	miR-517b	miR-520f		mir-182
	miR-517c	miR-520 g		miR-221
	miR-518b	miR-520 h
	miR-518f
	miR-525
Tumour Suppressor miRNA	Downregulated		Upregulated	Downregulated
	miR-148a		miR-424	miR-26a
			miR-27b	miR-31
			miR-28	miR-125b
			miR-30d
			miR-149
			miR-331
NTera-2	hESC undifferentiated		hESC differentiated
OncomiR	Downregulated		Upregulated	Downregulated
	miR-18a		miR-193b	miR-22
	miR-19a			miR-125b
	miR-19b			miR-221
	miR-367			miR-222
	miR-374
	miR-517c
Tumour Suppressor miRNA			Upregulated	Downregulated
			miR-145	miR-22
			miR-193b	miR-31
				miR-125b
				miR-34c

The individual titles ‘Downregulated’ and ‘Upregulated’ indicate the differential expression of each miRNA after SOX2 knock-down in either 2102Ep or NTera-2 cell lines or both.

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ISSN: 1471-2164

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