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Table 3 MiRNAs with SOX2-binding sites in hESCs which were deregulated in 2102Ep and NTera-2 cells

From: An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines

  Precursor Mature miRNA Fold-change Distance to TSS Expression EMT/MET Validated targets × hECC data
2102Ep hsa-mir-9-2 miR-9* 5.16 1887   
hsa-mir-9-2 miR-9 3.83 1887 Up in EMT [80] CDX2, ID2
hsa-mir-181a-2 miR-181a-2* 3.05 -467   
hsa-mir-424 miR-424 2.87 3042 Up in EMT [81]  
hsa-mir-301a miR-301 1.78 55   
hsa-mir-182 miR-182 -2.08 -4286 Up in MET [82] RARG, SNAI2
hsa-mir-942 miR-942 -2.10 -126   
hsa-mir-183 miR-183* -2.32 -4286   
hsa-mir-183 miR-183 -2.90 -4286 Down in EMT [83] SNAI2
hsa-mir-135b miR-135b* -3.04 4448   
hsa-mir-766 miR-766 -5.04 -1234   
NTera-2 hsa-mir-19b-2 miR-19b -1.35 -932   PRUNE2
hsa-mir-22 miR-22 -1.58 -186 Up in EMT [84]  
hsa-mir-324 miR-324-5p -1.91 -2058   AHNAK
hsa-mir-124-2 miR-124 -1.98 -5 Down in EMT [85]  
hsa-mir-22 miR-22* -2.02 -186   
hsa-mir-7-1/7-3 miR-7 -2.27 -2262 Down in EMT [86]  
hsa-mir-135b miR-135b* -2.33 4448   
hsa-mir-135b miR-135b -2.56 4448   
hsa-mir-181a-2 miR-181a -2.61 -467 Up in EMT [87] NANOG
hsa-mir-577 miR-577 -3.31 1455   
hsa-mir-181a-2 miR-181a-2* -4.47 -467   
hsa-mir-1251 miR-1251 -7.90 1717