Table 3 Excerpt of gene ontology (GO) cluster classification

Cluster 1 (Translation and energy metabolism)

GO:0031145

2.64E-004

7

59

Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

GO:0043161

2.24E-004

8

76

Proteasomal ubiquitin-dependent protein catabolic process

GO:0006511

3.08E-003

10

165

Ubiquitin-dependent protein catabolic process

GO:0044265

8.83E-004

15

274

Cellular macromolecule catabolic process

GO:0044260

2.60E-009

81

2044

Cellular macromolecule metabolic process

GO:0043170

1.84E-003

112

4217

Macromolecule metabolic process

GO:0006414

9.54E-049

41

78

Translational elongation

GO:0006412

2.67E-027

48

326

Translation

GO:0043284

3.35E-004

61

1871

Biopolymer biosynthetic process

GO:0009059

1.31E-004

72

2251

Macromolecule biosynthetic process

GO:0044249

2.86E-004

68

2142

Cellular biosynthetic process

GO:0009058

1.95E-003

76

2627

Biosynthetic process

GO:0044237

5.08E-003

128

5073

Cellular metabolic process

GO:0010467

1.39E-004

74

2337

Gene expression

GO:0009987

2.55E-004

184

7730

Cellular process

GO:0006120

3.76E-003

4

30

Mitochondrial electron transport, NADH to ubiquinone

GO:0042775

1.27E-004

6

37

Organelle ATP synthesis coupled electron transport

GO:0006119

1.90E-004

7

56

Oxidative phosphorylation

GO:0006096

9.71E-003

4

39

Glycolysis

GO:0006091

5.24E-005

14

187

Generation of precursor metabolites and energy

Cluster 2 (Ubiquitination)

GO:0051437

4.62E-005

8

61

Positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle

GO:0043085

2.93E-003

13

249

Positive regulation of catalytic activity

GO:0051436

2.37E-004

7

58

Negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle

GO:0043086

8.56E-003

8

134

Negative regulation of catalytic activity

Cluster 3 (Interspecies interaction)

GO:0044419

1.18E-004

13

177

Interspecies interaction between organisms

GO:0051704

5.88E-004

17

321

Multi-organism process

Cluster 4 (Apoptosis)

GO:0006916

1.15E-003

9

120

Anti-apoptosis

GO:0043066

4.15E-003

10

172

Negative regulation of apoptosis

GO:0051093

6.73E-003

12

244

Negative regulation of developmental process

GO:0042981

4.69E-003

17

390

Regulation of apoptosis

GO:0006915

6.48E-003

22

575

Apoptosis

GO:0050793

7.01E-003

22

579

Regulation of developmental process

Cluster 5 (Cytoskeleton organization)

GO:0030036

2.25E-003

10

158

Actin cytoskeleton organization and biogenesis

GO:0030029

1.32E-003

11

173

Actin filament-based process

GO:0007010

6.17E-003

16

368

Cytoskeleton organization and biogenesis