Table 4 Differentially expressed genes between WT and Scnn1b -Tg whole lungs
Gene Name | PND 0 | PND 3 | PND 10 | PND 42 | ||||
|---|---|---|---|---|---|---|---|---|
Fold- Change | FDR p-value | Fold-Change | FDR p-value | Fold-Change | FDR p-value | Fold-Change | FDR p-value | |
Scnn1b | 11.7 | 8.47E-05 | 14.8 | 2.23E-05 | 14.0 | 3.10E-05 | 10.4 | 2.38E-05 |
Ttr | 1.5 | Â | 1.4 | Â | 2.2 | 1.98E-02 | 1.8 | Â |
9930013L23Rik | 1.2 | Â | -1.2 | Â | -2.2 | 4.20E-02 | 1.2 | Â |
Thbs2 | -1.0 | Â | -1.1 | Â | -2.6 | 6.25E-05 | 1.1 | Â |
Fabp1 | -1.0 | Â | -1.1 | Â | -1.1 | Â | -2.1 | 3.69E-04 |
Chst4 | 1.1 | Â | 1.0 | Â | 1.1 | Â | -2.1 | 1.35E-04 |
Scgb1c1 | -1.5 | Â | -1.2 | Â | -1.2 | Â | -2.3 | 4.87E-02 |
Cyp2a4 | -1.0 | Â | 1.1 | Â | 1.1 | Â | -2.4 | 1.91E-02 |
Sult1d1 | -1.1 | Â | -1.1 | Â | 1.1 | Â | -2.8 | 9.46E-03 |
Chi3l4 | -1.1 | Â | -1.1 | Â | -3.1 | 5.78E-02 | 30.1 | 5.77E-07 |
Clca3 | -1.0 | Â | 1.0 | Â | -5.8 | 6.25E-05 | 21.9 | 4.37E-08 |
Slc26a4 | -1.1 | Â | -1.2 | Â | -2.0 | 4.26E-01 | 10.3 | 7.47E-05 |
Muc5ac | 1.0 | Â | 1.1 | Â | -2.6 | 1.23E-02 | 2.6 | 2.34E-03 |
Phxr4 | 2.2 | 3.64E-02 | -1.0 | Â | -1.1 | Â | 1.0 | Â |
Gm22843 | 2.1 | 2.67E-02 | 1.0 | Â | 1.0 | Â | -1.0 | Â |
Abp1 (Aoc1) | 1.2 | Â | 2.8 | 2.41E-02 | 2.3 | 1.66E-02 | 1.1 | Â |
Gpnmb | 1.1 | Â | 2.1 | 7.69E-01 | 5.5 | 5.45E-02 | 13.4 | 7.53E-04 |
Bst1 | -1.0 | Â | 1.4 | Â | 2.8 | 2.02E-02 | 1.6 | Â |
Sncg | 1.1 | Â | -1.0 | Â | 2.4 | 1.39E-02 | 1.2 | Â |
Wdr16 | -1.2 | Â | 1.6 | Â | 2.1 | 1.23E-02 | 1.2 | Â |
Anxa8 | -1.1 | Â | 1.3 | Â | 2.1 | 1.41E-02 | 1.1 | Â |
Clu | 1.1 | Â | 1.4 | Â | 2.1 | 1.40E-02 | 1.1 | Â |
H19* | -1.3 | Â | -1.0 | Â | 2.6 | 1.46E-02 | 1.0 | Â |
Mmp12 | -1.0 | Â | -1.1 | Â | 5.4 | 4.53E-03 | 34.8 | 2.96E-07 |
Cd177 | -1.2 | Â | 1.8 | Â | 6.6 | 2.69E-02 | 11.3 | 1.52E-03 |
Ctsk | 1.0 | Â | 1.4 | Â | 2.7 | 1.41E-02 | 9.5 | 1.19E-06 |
Pigr | 1.1 | Â | 1.5 | Â | 2.3 | 2.92E-01 | 4.9 | 3.40E-03 |
Gp49a | 1.1 | Â | 1.2 | Â | 2.3 | 4.63E-01 | 4.8 | 1.94E-02 |
Lilrb4 | 1.1 | Â | 1.3 | Â | 2.4 | 3.56E-01 | 4.2 | 1.82E-02 |
Ccl9 | -1.2 | Â | 1.0 | Â | 2.0 | 5.04E-01 | 3.9 | 1.79E-02 |
Mcoln3 | -1.0 | Â | 1.1 | Â | 2.0 | 1.67E-01 | 3.4 | 2.13E-03 |
Cd68 | -1.1 | Â | 1.3 | Â | 2.1 | 1.14E-01 | 2.8 | 6.81E-03 |
Gp2 | -1.0 | Â | -1.0 | Â | 1.8 | Â | 9.9 | 2.63E-04 |
Arg1 | -1.2 | Â | -1.3 | Â | 1.7 | Â | 8.9 | 6.84E-03 |
BC048546 | -1.1 | Â | 1.1 | Â | 1.8 | Â | 7.5 | 7.47E-05 |
Ear11 | -1.1 | Â | 1.0 | Â | -1.5 | Â | 7.2 | 4.73E-06 |
Awat1 | 1.0 | Â | 1.0 | Â | 1.0 | Â | 6.6 | 3.59E-03 |
Ch25h | -1.0 | Â | -1.2 | Â | 1.4 | Â | 6.2 | 1.30E-04 |
Chi3l3 | 1.1 | Â | 1.3 | Â | -1.5 | Â | 5.8 | 9.46E-03 |
Cxcr1 | 1.0 | Â | -1.0 | Â | 1.2 | Â | 5.7 | 9.66E-04 |
Bcl2a1d | -1.2 | Â | -1.1 | Â | -1.3 | Â | 5.4 | 1.91E-02 |
Retnla (Fizz1) | -1.4 | Â | -1.2 | Â | -1.9 | Â | 5.0 | 4.84E-02 |
Itgax | -1.1 | Â | -1.3 | Â | 1.6 | Â | 4.4 | 4.59E-03 |
Igk-V1 | -1.0 | Â | -1.2 | Â | 1.0 | Â | 3.9 | 2.64E-02 |
Fbp1 | -1.2 | Â | -1.1 | Â | -1.4 | Â | 3.8 | 8.44E-05 |
Chia | -1.1 | Â | -1.2 | Â | -1.3 | Â | 3.5 | 9.69E-03 |
Ccl6 | -1.0 | Â | 1.3 | Â | 1.2 | Â | 3.5 | 4.13E-02 |
Ly75 | 1.0 | Â | -1.1 | Â | 1.6 | Â | 3.3 | 7.53E-04 |
Ighv8-12 | 1.1 | Â | -1.1 | Â | -1.1 | Â | 3.2 | 1.62E-06 |
Tm4sf19 | 1.0 | Â | 1.0 | Â | 1.1 | Â | 3.2 | 3.91E-05 |
Slc39a2 | 1.1 | Â | -1.1 | Â | 1.7 | Â | 3.2 | 3.42E-02 |
Kynu | 1.0 | Â | 1.2 | Â | 1.1 | Â | 3.0 | 5.52E-03 |
Ms4a8a | -1.0 | Â | -1.0 | Â | 1.3 | Â | 3.0 | 4.18E-04 |
Reg3g | -1.3 | Â | 1.7 | Â | 1.7 | Â | 3.0 | 4.08E-02 |
Csf2rb | -1.1 | Â | 1.3 | Â | 1.9 | Â | 3.0 | 2.08E-02 |
Mgl2 | -1.0 | Â | -1.0 | Â | -1.6 | Â | 2.9 | 4.19E-04 |
Slc7a2 | -1.1 | Â | 1.2 | Â | 1.1 | Â | 2.9 | 9.46E-03 |
Cd84 | -1.1 | Â | -1.0 | Â | 1.4 | Â | 2.9 | 1.53E-03 |
F7 | -1.2 | Â | 1.3 | Â | 1.7 | Â | 2.9 | 1.94E-02 |
Gla | -1.2 | Â | 1.4 | Â | 1.3 | Â | 2.7 | 7.90E-03 |
Itgb2 | -1.3 | Â | 1.1 | Â | 1.7 | Â | 2.7 | 1.66E-02 |
Mmp19 | -1.0 | Â | 1.3 | Â | 1.1 | Â | 2.6 | 3.25E-02 |
Tbxas1 | -1.3 | Â | 1.1 | Â | 1.2 | Â | 2.6 | 2.76E-03 |
Lrp12 | -1.1 | Â | -1.1 | Â | 1.2 | Â | 2.6 | 2.38E-05 |
Bcl2a1a | 1.1 | Â | -1.1 | Â | 1.2 | Â | 2.6 | 1.27E-02 |
Slc6a20a | 1.1 | Â | -1.0 | Â | 1.2 | Â | 2.5 | 6.17E-03 |
Cd200r4 | -1.1 | Â | -1.0 | Â | 1.5 | Â | 2.5 | 1.52E-03 |
Rbp4 | -1.4 | Â | -1.1 | Â | -1.0 | Â | 2.4 | 1.94E-02 |
Lipa | -1.3 | Â | 1.1 | Â | 1.1 | Â | 2.4 | 5.62E-04 |
Bcl2a1b | 1.1 | Â | -1.0 | Â | 1.2 | Â | 2.4 | 2.06E-02 |
Il7r | -1.0 | Â | 1.0 | Â | 1.5 | Â | 2.4 | 3.71E-02 |
Fn1 | -1.0 | Â | -1.2 | Â | -1.4 | Â | 2.3 | 4.24E-02 |
Mrc1 | -1.0 | Â | 1.1 | Â | 1.1 | Â | 2.3 | 1.14E-02 |
Ctsd | -1.1 | Â | 1.2 | Â | 1.4 | Â | 2.3 | 4.87E-04 |
Hc | 1.1 | Â | -1.1 | Â | -1.3 | Â | 2.1 | 1.94E-02 |
Ptgir | -1.0 | Â | 1.1 | Â | -1.1 | Â | 2.1 | 1.91E-02 |
Lilra5 | 1.0 | Â | -1.2 | Â | 1.1 | Â | 2.1 | 3.40E-03 |
Dhcr7 | -1.1 | Â | -1.1 | Â | 1.1 | Â | 2.1 | 2.55E-02 |
Tnfrsf26 | -1.0 | Â | 1.0 | Â | 1.2 | Â | 2.1 | 1.29E-02 |
Fnip2 | 1.1 | Â | 1.4 | Â | 1.2 | Â | 2.1 | 1.33E-02 |
Acp5 | -1.0 | Â | 1.0 | Â | 1.7 | Â | 2.1 | 9.46E-03 |
Myo5a | 1.1 | Â | -1.2 | Â | 1.0 | Â | 2.0 | 2.85E-02 |
Syk | -1.0 | Â | 1.1 | Â | 1.2 | Â | 2.0 | 1.68E-02 |
Fetub | -1.1 | Â | 1.3 | Â | 1.5 | Â | 2.0 | 3.92E-02 |