PND 3 vs PND 0 | PND 10 vs PND 3 | PND 42 vs PND 10 | |||
---|---|---|---|---|---|
WT | Scnn1b-Tg | WT | Scnn1b-Tg | WT | Scnn1b-Tg |
UP-REGULATED | |||||
GO:0007059 Chromosome segregation | GO:0019882 Antigen processing and presentation | NONE* | NONE* | GO:0007157 Heterophilic cell-cell adhesion | GO:0032944 Regulation of mononuclear cell proliferation |
GO:0000070 Mitotic sister chromatid segregation | GO:0007059 Chromosome segregation | Â | Â | NONE* | GO:0070663 Regulation of leukocyte proliferation |
GO:0000819 Sister chromatid segregation | GO:0048002 Antigen processing and presentation of peptide antigen | Â | Â | Â | GO:0050670 Regulation of lymphocyte proliferation |
GO:0006310 DNA recombination | GO:0071346 Cellular response to interferon-gamma | Â | Â | Â | GO:0045058 T cell selection |
GO:0006302 Double-strand break repair | GO:0032615 Interleukin-12 production | Â | Â | Â | GO:0050870 Positive regulation of T cell activation |
GO:0007067 Mitosis | GO:0032655 Regulation of interleukin-12 production | Â | Â | Â | GO:0042129 Regulation of T cell proliferation |
GO:0006281 DNA repair | GO:0045087 Innate immune response | Â | Â | Â | GO:0006720 Isoprenoid metabolic process |
GO:0048285 Organelle fission | GO:0002474 Antigen processing and presentation of peptide antigen via MHC class I | Â | Â | Â | GO:0051251 Positive regulation of lymphocyte activation |
GO:0000280 Nuclear division | GO:0032606 Type I interferon production | Â | Â | Â | GO:0048002 Antigen processing and presentation of peptide antigen |
GO:0000725 Recombinational repair | GO:0032479 Regulation of type I interferon production | Â | Â | Â | GO:0070661 Leukocyte proliferation |
DOWN-REGULATED | |||||
GO:0060541 Respiratory system development | GO:0060485 Mesenchyme development | GO:0035456 Response to interferon-beta | GO:0030595 Leukocyte chemotaxis | GO:0007059 Chromosome segregation | GO:0007067 Mitosis |
GO:0030324 Lung development | GO:0030324 Lung development | GO:0035458 Cellular response to interferon-beta | GO:0050900 Leukocyte migration | GO:0007067 Mitosis | GO:0000280 Nuclear division |
GO:0030323 Respiratory tube development | GO0030323 Respiratory tube development | GO:0045087 Innate immune response | GO:0045087 Innate immune response | GO:0000280 Nuclear division | GO:0007059 Chromosome segregation |
GO:0060485 Mesenchyme development | GO:0060541 Respiratory system development | GO:0045851 pH reduction | GO:0006954 Inflammatory response | GO:0048285 Organelle fission | GO:0048285 Organelle fission |
GO:0002009 Morphogenesis of an epithelium | GO:0001657 Ureteric bud development | GO:0051607 Defense response to virus | GO:0006955 Immune response | GO:0000070 Mitotic sister chromatid segregation | GO:0000819 Sister chromatid segregation |
GO:0048762 Mesenchymal cell differentiation | GO:0055123 Digestive system development | GO:0051453 Regulation of intracellular pH | GO:0060326 Cell chemotaxis | GO:0000819 Sister chromatid segregation | GO:0033700 Phospholipid efflux |
GO:0048729 Tissue morphogenesis | GO:0048762 Mesenchymal cell differentiation | GO:0051452 Intracellular pH reduction | GO:0048520 Positive regulation of behavior | GO:0000278 Mitotic cell cycle | GO:0000070 Mitotic sister chromatid segregation |
GO:0003007 Heart morphogenesis | GO:0048562 Embryonic organ morphogenesis | GO:0048525 Negative regulation of viral process | GO:0032103 Positive regulation of response to external stimulus | GO:0000725 Recombinational repair | GO:0007052 Mitotic spindle organization |
GO:0048562 Embryonic organ morphogenesis | GO:0048565 Digestive tract development | GO:0030641 Regulation of cellular pH | GO:0002690 Positive regulation of leukocyte chemotaxis | GO:0007052 Mitotic spindle organization | GO:0070301 Cellular response to hydrogen peroxide |
GO:0010632 Regulation of epithelial cell migration | GO:2000736 Regulation of stem cell differentiation | GO:0002224 Toll-like receptor signaling pathway | GO:0002687 Positive regulation of leukocyte migration | GO:0000724 Double-strand break repair via homologous recombination | GO:0090068 Positive regulation of cell cycle process |