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Figure 1 | BMC Genomics

Figure 1

From: Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza

Figure 1

Tanshinone production is a major metabolic response of S. miltiorrhiza hairy root cultures to induction. (A and B) Plot of the first two components, accounting for almost 86% of the total variability, from principle component analysis (PCA) of the detected S. miltiorrhiza metabolites. (A) Shown are compounds whose peak accumulation occurs at the indicated time, demonstrating that the first principal component mainly reflects metabolites produced at later time points, whereas the second principal component represents changes at earlier time points. (B) The five compounds most representative to the first principal component are tanshinones, namely tanshinone IIA, cryptotanshinone, 15,16-dihydrotanshinone, trijuganone B, and dihydrotanshinone I. (C) Plots demonstrating the increasing accumulation of miltirone and the five compounds identified in panel B over time (error bars represent standard error of the mean, SEM). Also shown are the corresponding structures.

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