Figure 6

Candidate cytochrome P450 genes for tanshinone biosynthesis. (A) Hierarchically clustered heat map for the 85 DE cytochrome P450 (CYP) genes reflecting log-2 transformed expression fold changes relative to the control). (B) Proportion of up-regulated genes from each CYP clan. (C) Distribution of the 39 up-regulated CYPs in clans, as well as the family distribution of the 26 members from the CYP71 clan. (D) Histogram plot of the fold induction at each time point for each of the 8 CYP genes exhibiting continuously increasing expression levels following induction.