Table 2 Identification of signaling pathways enriched in more than one cell line
Treatment | Intersection | Enriched KEGG pathways | Biocarta pathways |
|---|---|---|---|
β-catenin RNAi | DLD1/SW480 | Endocytosis | mCalpain pathway |
Insulin signaling pathway | CREB pathway | ||
Lysosome | IGF1R pathway | ||
FC gamma R mediated phagocytosis | |||
Apoptosis | |||
Regulation of actin cytoskeleton | |||
Glycerolipid metabolism | |||
Focal adhesion | |||
Aldosterone regulated sodium reabsorption | |||
DLD1/LS174T | PPAR signaling pathway | – | |
Metabolism of xenobiotics by cytochrome P450 | |||
Butanoate metabolism | |||
SW480/LS174T | Complement and coagulation cascades | ||
Histidine metabolism | |||
Ether lipid metabolism | |||
NOD like receptor signaling pathway | |||
DLD1/SW480/LS174T | Steroid hormone biosynthesis | – | |
β-galactosidase RNAi | DLD1/SW480 | Glycine serine and threonine metabolism | – |
Renin angiotensin system | |||
DLD1/LS174T | DNA replication | ATRBRCA pathway | |
Base excision repair | |||
Mismatch repair | |||
Homologous recombination | |||
Cell cycle | |||
Nucleotide excision repair | |||
Pyrimidine metabolism | |||
RNA polymerase | |||
RNA degradation | |||
Spliceosome | |||
SW480/LS174T | Basal cell carcinoma | – | |
DLD1/SW480/LS174T | – |