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Table 1 Relative enrichment of the motif for the ChIP-ed TF in tamoxifen-treated and untreated MCF10A-ER-Src cells

From: Differential motif enrichment analysis of paired ChIP-seq experiments

     

Fisher E-value

ChIP

A

B

Motif

A vs. B

B vs. A

FOS

Tam 4 hr

EtOH

Fos

884

1.24e-87

FOS

Tam 12 hr

EtOH

Fos

884

4.07e-59

FOS

Tam 36 hr

EtOH

Fos

884

1.24e-06

MYC

Tam 4 hr

EtOH

Myc

884

4.95e-05

STAT3

Tam 12 hr

EtOH

Stat3

884

2.74e-11

STAT3

Tam 36 hr

EtOH

Stat3

884

1.15e-10

  1. The table columns show the name of the ChIP-ed transcription factor (“ChIP”), the names of the two ChIP-seq peak region sets (columns “A” and “B”), the name of the known (JASPAR) motif for the ChIP-ed TF (“Motif”) and the Fisher E-value (adjusted for 884 known motifs) reported by CentriMo when the first-named peak region set is used as the “treatment” and the second as the “control”. CentriMo site probability curves for the cases in bold font and the JASPAR IDs of the known motifs are given in Figure 1.