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Table 4 Central enrichment of STAT, FOS, MYC and NF- κ B motifs in ChIP-seq peaks in tamoxifen-treated MCF10A-ER-Src cells

From: Differential motif enrichment analysis of paired ChIP-seq experiments

FOS

4 hr

 

12 hr

 

36 hr

 

Motif

E-value

Motif

E-value

Motif

E-value

JDP2_full

1

JDP2_full

1

JDP2_full

1

Fos

4

Fos

4

Fos

4

Mycn

125

Stat3

112

Mycn

117

Stat3

130

Mycn

122

Stat3

136

NFKB1_DBD

322

NFKB2_DBD

282

NFKB1_DBD

402

MYC

 

STAT3

4 hr

 

12 hr

 

36 hr

 

Motif

E-value

Motif

E-value

Motif

E-value

JDP2_full

1

STAT1

1

STAT1

1

Mycn

3

Fos

6

Fos

6

Fos

11

NF-kappaB

79

NF-kappaB

110

Stat3

181

Mycn

213

Mycn

221

NFKB2_DBD

317

    
  1. The table shows the name and rank (out of 884) of the most significantly enriched motif from each of the four TF families in the peaks of the ChIP-ed TF (top lines) in MCF10A-ER-Src cells treated with tamoxifen for the given time (second lines). The top-ranking motif is also shown even if it is not from one of the four TF families. Rank is based on the CentriMo (non-differential) central enrichment E-value.